復仇者聯盟以及隨后影響深遠的紐約之戰(zhàn)，讓外星人和超能力者不再是坊間傳說的秘密。紐約之戰(zhàn)過后，世界格局即將重新洗牌，野心家們則蠢蠢欲動，神盾局面臨前所未有的挑戰(zhàn)。在此危急關頭，一度傳聞死于紐約的特工菲爾·科爾森探員（克拉克.

　　As Leo's replacement Thomas Chamberlain arrives Nikki investigates the murders of Rachel Freedman, shot in the head, and her little autistic son Nathan, who was poisoned. Nikki rejects policewoman Anne Burchett's theory that Rachel killed them both but is perturbed when an impostor, claiming to be Rachel's sister, visits the morgue. At the same time the disfigured corpse of Eva Liron is discovered, killed with the same poison as Nathan. She had been the nanny to French hot shot footballer Isaac Dreyfus and was planning to blackmail him over a sex tape of them both. Jewish Isaac is a controversial figure due to his anti-Muslim sentiments but he denies ant part in the murders. Then another victim, Isaac's agent Mousa, is discovered dead.

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本劇改編自同名小說。26歲的研究生小森冰雨（伊藤健太郎 飾）愛上了比自己大一輪的42歲女性水野伊麻（栗山千明 飾）。超越年齡差異的相互吸引中，冰雨想要跨出一步，伊麻告訴他的是“和兩個戀人一起生活”的事實。在全員同意并相互理解的基礎上貫徹“復數戀愛”這一愛的伊麻、對這種愛的形式感到困惑的冰雨、以及伊麻的46歲戀人·風間到（丸山智己 飾）和36歲的空久保亞夫（千賀健永 飾）之間不被常識所接受的戀愛模樣，將在本劇中得到刻畫。此外，伊麻的友人·絹香因與道德騷擾的丈夫的關系而煩惱，伊麻的女兒·千夏等人的故事也糾纏在一起，各自的愛情故事由此展開。