該劇以當代北京為背景，講述了孫心、孫想這對性格迥然不同的姐妹，在自由拼搏與平淡安穩(wěn)中忠于本心，追尋美好生活的故事 。

　　林小盼幼時父母離婚，隨父去日本留學(xué)，畢業(yè)于日本短期大學(xué)家政專業(yè)，看似傻白甜，其實是一位執(zhí)拗熱血、正義感爆棚的元氣少女。她父親林有碩寵愛女兒，在日本經(jīng)營中華料理店。小盼一心想跟男友周之偉結(jié)婚，不顧父親反對、不嫌對方窮苦，卻沒想到對方竟然逃婚！為尋其逃婚原因她追回上海，誤打誤撞接下清潔大樓的工作，從此揭開家政生涯的序幕，并結(jié)識了喪妻之痛的左飛，開始新的戀情。負責家政中介所的方嵐阿姨滿面笑容、活力四射，渾身一股颯爽之氣。方嵐慧眼識珠找到小盼，一見如故，都認為真善美高于一切，賺錢次要，主要是幫家政員找到生活意義。小盼從初級家政員，逐步成長為具備統(tǒng)籌管理能力的高級家政人才，被大家稱為“天才管家”。她因此受到鼓舞，著手創(chuàng)辦“小盼到家”的家政APP，嘗試用互聯(lián)網(wǎng)思維管理傳統(tǒng)的家政員，家政從此進入新時代。

　　該劇以1927年“四·一五”反革命政變?yōu)殚_篇，講述了佛山中共地下黨員陳氏夫婦為掩護同志撤離而慘遭殺害，老大陳山河（楊爍 飾）、老二陳青衛(wèi)（張翰 飾）以及幼女陳立夏（郭曉婷 飾）兄妹三人也因此天各一方的故事。多年后兄妹三人分別在粵藥、粵菜、粵劇方面各有所成，揚名廣州。因緣際會下，骨肉終得團聚。國難當頭之際，兄妹三人恪守本心，用一腔熱血譜寫出抗日風云的壯麗篇章。

　　炎沛湖（蘇玉華 飾）是含著金湯匙出生的千金大小姐，在即將和戀人張至凱（黃智賢 飾）步入婚姻殿堂之際，她被控謀殺而關(guān)入了監(jiān)獄，之后，炎沛湖意外的遇見了失散多年的妹妹蘇菲（唐寧 飾）和大姐江麗雅（田蕊妮 飾），得知了炎沛湖的冤情，蘇菲和江麗雅決定聯(lián)手還炎沛湖一個清白。
　　江麗雅意外得知自己患上了不治之癥，命不久矣，憐惜炎沛湖的她決定頂替妹妹之名，替她坐牢。獨自奮戰(zhàn)在調(diào)查事件真相第一線的蘇菲發(fā)現(xiàn)江麗雅的絕癥竟然是炎沛湖一手策劃的陰謀，失望的她找到了江麗雅，要幫助她越獄。炎沛湖機關(guān)算盡，但最終卻失去了一生摯愛。

　　李子京（尹晶喜 飾）的養(yǎng)母金培德（樸海美 飾）不務(wù)正業(yè)好吃懶做，為了滿足養(yǎng)母的各種非分要求，李子京年紀輕輕就負債累累，為了還債，她在課余時間找了一份化妝師的兼職，用以補貼家用。
　　在工作中，李子京結(jié)識了名為清河（趙延宇 飾）的演員，隨著時間的推移，兩人之間產(chǎn)生了真摯的感情，漸漸走到了一起，然而，清河的真實身份，竟然是金培德的弟弟。李子京和清河之間的戀情牽扯出了一段關(guān)于李子京身世的悲慘往事，當金培德得知這一切之后，便想方設(shè)法要將她和弟弟分開。李子京的親生母親一直在尋找女兒的蹤跡，想要彌補自己曾經(jīng)遺棄的的過錯。

　　After spending the summer with his mother in Philadelphia, Dawson returns to Capeside and meets a beautiful, outgoing, young woman, named Eve Whitman, on the bus from Philadelphia. Eve soon brings trouble to Dawson's ho-hum life when he accidentally wrecks his father's boat during an outing with her and tries to come up with $3,000 to repair it before Mitch finds out. So, Eve helps out by throwing a rave party at the Leery house with strippers from the club she works at. Meanwhile, Joey, who has frozen Dawson out all summer for forcing her to rat out her father, realizes that she still has feelings for him again when they meet during the first day back at Capeside High as juniors. While working at the Capeside Marina, Joey deals with the come-ons from her sexist boss Rob Logan. Jen gets more than she bargained for when she tries out for Capeside High's cheer leading squad and faces off in a war-of-wits against the mean-spirited head cheerleader, and acquires her position. Also, Mitch gets a new job as Capeside High's varsity football coach, and a new charismatic, but very stern, principal, named Howard Green, arrives to administrate the school.

　　Joey begins her first day at Worthington University where she is struggling in her beginners writing class taught by Professor David Wilder who criticizes her first essay about her and Dawson. Audrey Liddell, Joey's brash new roommate from Beverly Hills, proves to be more of an annoyance than a friend with her wild and crazy personality. Dawson, who's continuing his studies at USC with an internship in Hollywood, begins his job on a shaky start when he meets Todd Carr, an arrogant, egocentric, hack film director who gives Dawson a hard time. Meanwhile, Jen pays Pacey a visit, who's lying low as he docks his yacht in Boston Harbor after sailing away the summer. At nearby Boston Bay College, Jen and Jack are invited to their first fraternity party. They persuade Joey to come along with Audrey who seems to get along with Jen and Jack, much to Joey's surprise. Also, Jen meets Charlie, a bass player. She is rude to him, insulting him away, but deep inside feels strongly attracted to him.

　　During the summer, Pacey and Audrey rocked Los Angeles and spent time with her next door neighbors, the Osbournes, and Jack Osbourne even tags along with them to interview at Worthington. Jen spent her time in New York and got ecstatic to learn her parents are separating. Jack got dumped by Eric, but got over it. Joey spent her summer in Capeside doing a lot of reading, working and romancing. On their first week back at Boston Bay College, Jen is shocked to run into find that Grams Ryan has decided to go back to school. At Worthington, Joey experiences nothing but bad luck when she decides to enroll in an intermediate writing class taught by the liberal, but manipulative and cynical, Professor Greg Heston who does not hesitate to ridicule and embarrass Joey in front of the class with her lack of knowledge of the current book topic. Pacey and Jack move out of Grams' house and Pacey tries to get the perfect apartment, owned by a feisty, punk rock British woman, named Emma Jones, who works as a waitress in the local bar Hell's Kitchen. Also, Dawson is working on a new movie, a horror film titled "Wicked Dead" with him as the assistant director and the hack Todd Carr as director. When he finally gets together with Joey, he is the only one to have remembered her 20th birthday.

　　故事環(huán)繞捕殺伊邁德·穆格尼耶的行動。穆格尼耶被指為1980至90年代發(fā)生的兩宗美國駐貝魯特大使館爆炸案的主謀，后在2008年2月12日在大馬士革被汽車炸彈暗殺。